International Consensus Group on Research Integrity in Randomised Clinical Trials

2021

Professor Khalid Khan recently founded the multicountry multistakeholder expert panel consensus on how to improve clinical trial integrity. The panel experts represent 14 countries from 5 continents and cover in their experience the entire lifecycle of clinical trials.

 The stakeholders include trialists, ethicists, methodologists, statisticians, consumer representative, industry representative, systematic reviewers, funding body panel members, regulatory experts, authors, journal editors, peer-reviewers and advisors for resolving integrity concerns. The group has produced an international consensus statement on clinical trial integrity and post-publication issues in clinical trials.

TIPPS Review Group

2006 to 2011

Professor Khalid Khan established the TIPPS (Tests in Prediction of Preeclampsia’s Severity) Review Group to underpin collaborative work undertaken jointly by Academic Medical Centre, Amsterdam, Netherlands; Ramon y Cajal, Madrid, Spain; University of Birmingham Medical School, UK; and Keele University School of Medicine, Stoke-on-Trent, UK. This allowed for PhD supervision with multidisciplinary input. It also opened up career opportunities and led to seven peer-reviewed publications (2006-2011) that contributed to a PhD thesis (2011) and formed the basis for a large UK NIHR HTA grant called PREP (title: Development and validation of a Prediction model for Risk of complications in Early onset Pre-eclampsia; no. 09/22/163).

Finally, this research produced a HTA report and a prediction model for use within an application to assist patients and clinicians on the bedside. This journey ultimately contributed to the development of Dr Thangaratinam into a senior academic with appointment as Professor in UK higher education institutions (Queen Mary and Birmingham Universities) and she now enjoys a high profile within the specialty with many grants as Chief Investigator.

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